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Why take our celiac genetic predisposition test?

Our celiac disease genetic testing is the most accurate test you have to determine whether or not a person suffers from Celiac disease. Although blood antibody tests are available as well, these are only reliable if the person has been following a high gluten diet. If the person takes the blood antibody test and has not consumed any gluten shortly beforehand, then the test could provide false negative results. People already following a gluten-free diet will not find the answers they need using serology (blood) tests. Moreover, because the symptoms associated with Celiac disease are not necessarily specific to the disease, a genetic test is the only way of determining whether you have celiac disease if you have been on a gluten-free diet.

With celiac disease genetic testing, you can find out whether you are really Celiac at any time and at any age. Our test is ideal for confirming the presence of Celiac disease or even excluding it in cases where following a gluten-free diet does not result in a reduction of symptoms.

Our celiac disease genetic test is offered from £69 and results are ready in 10-15 working days from receipt of samples at the laboratory.

Our celiac predisposition test is really simple

We just require clients to collect samples using sterile mouth swabs found inside the kit we provide. There are no special conditions for mouth swab sampling except to avoid drinking, smoking and eating for 30 minutes before collecting your samples.

Results for celiac disease genetic testing

We offer two genetic testing options to guide you on your journey towards coeliac disease diagnosis:

Standard Test (£69): This cost-effective test analyzes the two essential genetic markers for coeliac disease, helping you: Simplify complex diagnoses, confirm positive serology or biopsy results and proactively manage your coeliac disease risk.

Extended Test (£99): Invest in comprehensive peace of mind with an analysis of 16 genetic markers. With this test you will rule out coeliac disease definitively with a negative result, get a better understanding of your individual susceptibility to coeliac disease and share valuable genetic information with your coeliac-affected family.

The Standard Test is ideal for initial screening or following up on unclear diagnoses. If you seek a more conclusive answer or want to understand your risk in more detail, the Extended Test provides valuable insights.

For an example of the standard test results, please click below:

 

 

For an example of the extended test results, please click below:

 

Frequent questions

What is celiac disease?

Celiac disease (sometimes also called Celiac Sprue) is an autoimmune disorder where the body is unable to break down a gluey protein found in wheat called “gluten”. If gluten cannot be broken down, the intestinal tract may be damaged over time and absorption of food compromised. Every time gluten is ingested, the body ends up fighting against itself and damaging itself. This means that a Celiac sufferer could exhibit a host of unpleasant symptoms as a direct or indirect effect of the disease. Malabsorption of food could lead to tiredness and fatigue, muscle wasting and nausea amongst many other symptoms.

What are the symptoms of Celiac Disease?

Symptoms of celiac disease vary from one person to the next, however these may include:

  • Failure to thrive (weight loss/failure to gain weight), particularly in children
  • Nausea
  • Diarrhoea
  • Steatorrhea (loose and greasy stool)
  • Dermatitis herpetiformis (severe skin rash)
  • Missed periods

A predisposition to Celiac disease but no symptoms?

Our genetic predisposition test for Celiac disease only establishes the likelihood that you will develop Celiac disease over the course of your life. This means that at the time of testing you may or may not be suffering from Celiac disease.

Can I take any other tests?

Besides a celiac disease genetic test, serology tests for celiac disease are available but to take this test you must be on a gluten-containing diet. If you have been on a gluten-free diet, you will need to start introducing gluten over a period of time in order to increase your levels of antibody. This test can cause some discomfort due to the fact it requires you to be on gluten containing diet – unlike our Celiac genetic test which can be done on people following a gluten-free diet. Whilst this may result in some discomfort, it is necessary to carry out this type of test. The test analyses the blood sample to verify the levels of the antibody known as Tissue Transglutaminase or tTG-IgA produced in response to gluten ingestion.We do not offer this test and suggest you speak to your doctor if you are interested in it.

Related Tests: Testing for Lactose Intolerance

Is your body unable to digest lactose, a type of sugar found in milk, cheese and other dairy products? If so, you might be lactose intolerant like a substantial part of the world’s population. homeDNAdirect offers lactose intolerance DNA testing for those who want to find out and start feeling better by regulating their diet.

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